Rosai-Dorfman Disease and Unusual Local Invasive Presentation

Rosai Dorfman disease--a clinico-pathological presentation.

Rosai Dorfman disease (RDD) or sinus histiocytosis with massive lymphadenopathy (SHML) is a rare disorder that typically manifests as lymphadenopathy and systemic symptoms. The authors report a 45 year old lady who presented with nasal mass and generalised lymphadenopathy. Histopathological examination demonstrated lymphophagocytosis (emperipolesis) consistent with a diagnosis of RDD. The clini...

Atypical presentation and dermoscopic evaluation of cutaneous Rosai-Dorfman Disease.

Rosai-Dorfman Disease.

A young male presented with recurrent neck swellings with initial leucocyte count of 16800/mm3, with non-caseating glands on ultrasonography neck. FNAC showed mixed cellularity with histiocytic and marked lymphophagocytosis as seen in Rosai Dorfman Disease. Immunohistochemistry demonstrated CD 25, Ki 67 and CD 68 in histiocytes. Her responded to supportive treatment alone.

Intrathoracic Rosai-Dorfman Disease

231 Received March 23, 2012; revision accepted for publication June 21, 2012. doi: 10.1620/tjem.227.231 Correspondence: Shingo Noguchi, M.D., Department of Respiratory Medicine, University of Occupational and Environmental Health, Iseigaoka, Yahatanishiku, Kitakyushu city, Fukuoka 807-8555, Japan. e-mail: [email protected] Intrathoracic Rosai-Dorfman Disease with Spontaneous Remission: A ...

Intracranial ROSAI-DORFMAN Disease

Rosai-Dorfman disease is a benign lymphohistiocytosis that often involve lymph nodes and present as massive lymphadenopathy with sinus histiocytosis. The disease is rarely associated with intracranial involvement. Herein, we report a 33-years-old man with recent onset of unconsciousness. According to his past medical history, he was suffering from frontal headache, ataxia and dizziness with no ...